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mc1r antibody solution  (Alomone Labs)


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    Structured Review

    Alomone Labs mc1r antibody solution
    (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the <t>MC1R</t> agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p<0.05). The unspecific melanocortin receptor agonist α-MSH did not have any significant effect (n = 9, n.s.) compared with untreated adriamycin mice. Results are presented as mean ± SEM.
    Mc1r Antibody Solution, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mc1r+antibody+solution/pmc03907561-87-19-5?v=Alomone+Labs
    Average 93 stars, based on 3 article reviews
    mc1r antibody solution - by Bioz Stars, 2026-07
    93/100 stars

    Images

    1) Product Images from "Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies"

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0087816

    (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p<0.05). The unspecific melanocortin receptor agonist α-MSH did not have any significant effect (n = 9, n.s.) compared with untreated adriamycin mice. Results are presented as mean ± SEM.
    Figure Legend Snippet: (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p<0.05). The unspecific melanocortin receptor agonist α-MSH did not have any significant effect (n = 9, n.s.) compared with untreated adriamycin mice. Results are presented as mean ± SEM.

    Techniques Used: Injection

    Gene expression of  MC1R  in human, rat and mouse kidney tissue.
    Figure Legend Snippet: Gene expression of MC1R in human, rat and mouse kidney tissue.

    Techniques Used: Expressing

    Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).
    Figure Legend Snippet: Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).

    Techniques Used: Western Blot, Expressing, Incubation, Blocking Assay, Cell Culture



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    Alomone Labs mc1r antibody solution
    (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the <t>MC1R</t> agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p<0.05). The unspecific melanocortin receptor agonist α-MSH did not have any significant effect (n = 9, n.s.) compared with untreated adriamycin mice. Results are presented as mean ± SEM.
    Mc1r Antibody Solution, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mc1r+antibody+solution/pmc03907561-87-19-5?v=Alomone+Labs
    Average 93 stars, based on 1 article reviews
    mc1r antibody solution - by Bioz Stars, 2026-07
    93/100 stars
      Buy from Supplier

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    (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p<0.05). The unspecific melanocortin receptor agonist α-MSH did not have any significant effect (n = 9, n.s.) compared with untreated adriamycin mice. Results are presented as mean ± SEM.

    Journal: PLoS ONE

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    doi: 10.1371/journal.pone.0087816

    Figure Lengend Snippet: (A) Five different doses of adriamycin, in the range of 5–10 mg/kg, were intravenously injected and the level of albuminuria was measured after 7 days. The urinary albumin-to-creatinine ratio (UACR) increased with increasing levels of adriamycin. (B) Albuminuria at day 7. Treatment with the MC1R agonist BMS-470539 did not reduce the level of albuminuria for the 8 mg/kg adriamycin dose, on the contrary it slightly increased albuminuria for the 10 mg/kg dose (n = 17–19, p<0.05). The unspecific melanocortin receptor agonist α-MSH did not have any significant effect (n = 9, n.s.) compared with untreated adriamycin mice. Results are presented as mean ± SEM.

    Article Snippet: An MC1R control peptide antigen (Alomone Labs, Ltd., Israel) was separately added at a 1∶1 weight ratio to the MC1R antibody solution before incubation to confirm antibody specificity.

    Techniques: Injection

    Gene expression of  MC1R  in human, rat and mouse kidney tissue.

    Journal: PLoS ONE

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    doi: 10.1371/journal.pone.0087816

    Figure Lengend Snippet: Gene expression of MC1R in human, rat and mouse kidney tissue.

    Article Snippet: An MC1R control peptide antigen (Alomone Labs, Ltd., Israel) was separately added at a 1∶1 weight ratio to the MC1R antibody solution before incubation to confirm antibody specificity.

    Techniques: Expressing

    Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).

    Journal: PLoS ONE

    Article Title: Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies

    doi: 10.1371/journal.pone.0087816

    Figure Lengend Snippet: Western blotting was performed in order to detect MC1R protein expression in mouse and human tissue. Left panel: incubation with a rabbit polyclonal MC1R antibody (Alomone Labs). Right panel: incubation with MC1R antibody and control blocking peptide antigen (BP) in order to show antibody specificity. A) mouse whole glomerular lysate, B) cultured wild type mouse podocytes and C) a human malignant melanoma cell line A375. MC1R protein expression was detected at the expected size of 37 kDa (left panel).

    Article Snippet: An MC1R control peptide antigen (Alomone Labs, Ltd., Israel) was separately added at a 1∶1 weight ratio to the MC1R antibody solution before incubation to confirm antibody specificity.

    Techniques: Western Blot, Expressing, Incubation, Blocking Assay, Cell Culture